Mechanism of improved intermediate temperature plasticity of nickel-base single crystal superalloy with hot isostatic pressing

In this work, we investigate the effect of hot isostatic pressing on the intermediate temperature tensile property of nickel-base single crystal superalloy.The experimental results indicate that the hot isostatic pressing improves the intermediate temperature plasticity of single crystal superalloy from 6.4% to 9.3%, but the yield strength remains

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Drug Repurposing as an Antitumor Agent: Disulfiram-Mediated Carbonic Anhydrase 12 and Anion Exchanger 2 Modulation to Inhibit Cancer Cell Migration

Disulfiram has been used in the treatment of alcoholism and exhibits an anti-tumor effect.However, the intracellular mechanism of anti-tumor activity of Disulfiram remains unclear.In this study, we focused on the modulatory role of Disulfiram via oncogenic factor carbonic anhydrase CA12 and its associated transporter anion exchanger AE2 in lung can

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